Dates Pollen Extract (Phoenix dactylifera L) as Infertility Therapy in Men

Devi Rahmadiani

  • Devi Rahmadiani Universitas Lampung
Keywords: date palm pollen, male infertility


Introduction Infertility is one of the problems faced by couples who want to have children. Infertility in a year occurs as much as 15% in couples who expect pregnancy. Aim; analyzed that the antioxidant content in DPP can counteract free radicals and prevent oxidative stress. Method; The analysis is carried out with a systematic literature review method by examining, identifying, assessing, and presenting it. Result; found various studies showing that DPP extract has an effect to prevent and treat infertility. Conclusion; that there is a decrease in sperm quality due to increased oxidative stress due to an imbalance of antioxidants and free radicals


Download data is not yet available.

Author Biography

Devi Rahmadiani, Universitas Lampung

Fakultas Kedokteran


Agarwal, A., Mulgund, A., Hamada, A., & Chyatte, M. R. (2015). A unique view on male infertility around the globe. Reproductive Biology and Endocrinology, 13(1).

Al-Kharage, R. (1982). Protective effects of Phoenix dactylifera (date palm) against cisplatin-induced genotoxicity. Food Science and Technology Abstract, 4, 331.

Al-Samarai, & Al-Salihi, F. G. (2016). Phytochemical constituents and nutrient evaluation of date palm (Phoenix dactylifera, L.) pollen grains. Tikrit Journal of Pure Science.

Al-Sanafi A, Bahaadeen E, Marbeen M, M. M. (2006). The effect of date palm pollens and zinc sulfate in the treatment of humans. Tikrit Journal of Pharmaceutical Sciences., 2, 31–34.

Anifandis, G., Bounartzi, T., Messini, C. I., Dafopoulos, K., Sotiriou, S., & Messinis, I. E. (2014). The impact of cigarette smoking and alcohol consumption on sperm parameters and sperm DNA fragmentation (SDF) measured by Halosperm®. Archives of Gynecology and Obstetrics, 290(4), 777–782.

Baharara, J., Amini, E., Salek-Abdollahi, F., Nikdel, N., & Asadi-Samani, M. (2015). Protective effect of date palm pollen (Phoenix dactylifera) on sperm parameters and sexual hormones in male NMRI mice exposed to low-frequency electromagnetic field (50 Hz). Journal of HerbMed Pharmacology.

Bahmanpour, S., Kavoosi, F., Talaei, T., & Panjehshahin, R. (2013). Effects of Date Palm (Phoenix Dactylifera) Gemmule Extract on Morphometric Parameters of Reproductive Tissues, Hormones and Sperm Quality in Rat. Anatomical Sciences.

Bahmanpour, S., Talaei, T., Vojdani, Z., Panjehshahin, M. R., Poostpasand, A., Zareei, S., & Ghaeminia, M. (2006). Effect of Phoenix dactylifera pollen on sperm parameters and reproductive system of adult male rats. Iranian Journal of Medical Sciences.

Daoud, A., Malika, D., Bakari, S., & Hfaiedh, N. (2019). Assessment of polyphenol composition, antioxidant and antimicrobial properties of various extracts of Date Palm Pollen ( DPP ) from two Tunisian cultivars. Arabian Journal of Chemistry, 12, 3075–3086.

Desai, N., Sharma, R., Makker, K., Sabanegh, E., & Agarwal, A. (2009). Physiologic and pathologic levels of reactive oxygen species in neat semen of infertile men. Fertility and Sterility.

Dohle, G. R., Colpi, G. M., Hargreave, T. B., Papp, G. K., Jungwirth, A., & Weidner, W. (2005). EAU guidelines on male infertility. European Urology.

Duarsa, G. W. K., Soebadi, D. M., Taher, A., Purnomo, B. B., Rasyid, N., Noegroho, B. S., … Rizaldi, F. (2015). Guideline Infertilitas Pria 2015. Ikatan Ahli Urologi Indonesia.

Durairajanayagam, D., Rengan, A. K., Sharma, R. K., & Agarwal, A. (2015). Sperm biology from production to ejaculation. In Unexplained Infertility: Pathophysiology, Evaluation, and Treatment (pp. 29–42). Springer New York.

Dutta, S., & Sengupta, P. (2018). Medicinal herbs in the management of male infertility. Journal of Pregnancy and Reproduction, 2(1).

El-far, A. H., Shaheen, H. M., Abdel-daim, M. M., Jaouni, S. K. Al, & Mousa, S. A. (2016). iMedPub Journals Date Palm (Phoenix dactylifera ): Protection and Remedy Food, 1–10.

El-Kashlan, A. M., Nooh, M. M., Hassan, W. A., & Rizk, S. M. (2015). Therapeutic potential of date palm pollen for testicular dysfunction induced by thyroid disorders in male rats. PLoS ONE.

El-Neweshy, M. S., El-Maddawy, Z. K., & El-Sayed, Y. S. (2013). Therapeutic effects of date palm (Phoenix dactylifera L.) pollen extract on cadmium-induced testicular toxicity. Andrologia.

Faleh, B. H., & Sawad, A. A. (2006). Effect of Date Palm Pollen Grains Extracts ( Phoenix dactylifera L ) on Spermatogenic Activity of Male Rabbits. J Al-Basrah Res, 5, 1–10.

Grafodatskaya, D., Cytrynbaum, C., & Weksberg, R. (2013). The health risks of ART. EMBO Reports.

Halliwell, B., & Gutteridge, J. M. C. (2007). Cellular responses to oxidative stress: adaptation, damage, repair, senescence, and death. In Free Radical Biology and Medicine.

Harris, I. D., Fronczak, C., Roth, L., & Meacham, R. B. (2011). Fertility and the aging male. Reviews in Urology, 13(4), e184-90. Retrieved from

Hassan, H. M. M. (2011). Chemical Composition and Nutritional Value of Palm Pollen Grains. Global Journal of Biotechnology & Biochemistry.

Hassan, W. A., El-kashlan, A. M., Mohamed, N. A., & Noha A. Ehssan. (2012). Egyptian date palm pollen ameliorates testicular dysfunction induced by cadmium chloride in adult male rats. Journal of American Sciences.

Jequier, A. M. (2000). WHO Manual for the Standardized Investigation and Diagnosis Of the Infertile Male. The Obstetrician & Gynaecologist, 2(4), 55–55.

Makker, K., Agarwal, A., & Sharma, R. (2009). Oxidative stress & male infertility. Indian Journal of Medical Research.

Marbeen, M. I., Al-snafi, A. E., Marbut, M. M., & Allahwerdy, I. Y. (2005). The probable therapeutic effects of date palm pollen in the treatment of male infertility. Tikrit Journal of Pltarruaceuticul Sciences.

Mehraban, F., Jafari, M., Akbartabar Toori, M., Sadeghi, H., Joodi, B., Mostafazade, M., & Sadeghi, H. (2014). Effects of date palm pollen (Phoenix dactylifera L.) and Astragalus ovinus on sperm parameters and sex hormones in adult male rats. Iranian Journal of Reproductive Medicine, 12(10), 705–712. Retrieved from

Meri, Z. B., Irshid, I. B., Migdadi, M., Irshid, A. B., & Mhanna, S. A. (2013). Does cigarette smoking affect seminal fluid parameters? A Comparative Study. Oman Medical Journal, 28(1), 12–15.

Moshfegh, F., Baharara, J., Namvar, F., Zafar-Balanezhad, S., Amini, E., & Jafarzadeh, L. (2016). Effects of date palm pollen on fertility and development of the reproductive system in female Balb/C mice. Journal of HerbMed Pharmacology.

Packer, L., Rimbach, G., & Virgili, F. (1999). Antioxidant activity and biologic properties of a procyanidin-rich extract from pine (Pinus Maritima) bark, pycnogenol. Free Radical Biology and Medicine.

Praptiwi, & Arti, D. W. K. (2017). Manfaat Buah kurma. Jurnal Berkala Ilmiah Kedokteran dan Kesehatan (Vol. 1). Retrieved from

Salman, I., Munazza, A., Hina, M. A., Tahir, S., Yasir, A., & Gul-E-, N. (2014). Evaluation of spermatogenesis in prepubertal albino rats with date palm pollen supplement. African Journal of Pharmacy and Pharmacology.

Sanger, W. G., & Friman, P. C. (1990). The fit of underwear and male spermatogenesis: A pilot investigation. Reproductive Toxicology, 4(3), 229–232.

Saraswati, A. (2015). Infertility. J Majority, 4, 5.

Tijani, K. H., Oyende, B. O., Awosanya, G. O., Ojewola, R. W., & Yusuf, A. O. (2014). Assessment of testicular volume: A comparison of fertile and sub-fertile West African men. African Journal of Urology.

Winarsih, H. (2007). Antioksidan Alami dan Radikal Bebas. Cetakan Kelima.

Yasir, A., Nasir, M., Munazza, A., Muhammad, T., Fan, Z., Di-Jie, L., … Ai-Rong, Q. (2014). Effect of date palm pollen on serum testosterone and the intra-testicular environment in male albino rats. African Journal of Pharmacy and Pharmacology.

How to Cite
Rahmadiani, D. (2021). Dates Pollen Extract (Phoenix dactylifera L) as Infertility Therapy in Men. Jurnal Ilmiah Kesehatan Sandi Husada, 10(1), 31-40.

Most read articles by the same author(s)

Obs.: This plugin requires at least one statistics/report plugin to be enabled. If your statistics plugins provide more than one metric then please also select a main metric on the admin's site settings page and/or on the journal manager's settings pages.