Physical Stability Test of Leaf Powder Ethanol Extract of Ciplukan Leaf (Physalis angulata L.) as Anti-Fungal

Sulfiyana H. Ambo Lau, Herman Herman

  • Sulfiyana H. Ambo Lau Akademi Farmasi Sandi Karsa
  • Herman Herman Akademi Farmasi Sandi Karsa
Keywords: Formulations, Physical Stability Test, Ciplukan leaves (Physalis angulata L.), Powder

Abstract

Ciplukan (Physalis angulata L.) is a seasonal herbaceous plant from the Solanaceae family which has many benefits, one of which is as an antifungal. Research has been carried out on the formulation and physical stability test of the ethanol extract of the leaves of Ciplukan (Physalis angulata L.) as anti-fungi. The goal is to find out that ciplukan leaves contain chemical substances that can inhibit the growth of fungi on the skin and can be formulated into powder preparations. This research is a laboratory experimental research. This research includes identification tests for alkaloids, flavonoids, saponins, steroids, and tannins. The powder formulations were FI (without extract), FII (extract 10%), and FIII (extract 20%). The stability test of the preparation includes the organoleptic test, homogeneity, fine degree, pH, adhesion, and hedonic test. The results of the research identified positive compounds containing alkaloids, flavonoids, saponins, and tannins. In the stability test, all formulations showed the results according to the literature, the hedonic test was not irritating and formula FII was preferred. The conclusion is that the ethanol extract of ciplukan leaves contains antifungal compounds and can be formulated into powder with good stability

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Author Biographies

Sulfiyana H. Ambo Lau, Akademi Farmasi Sandi Karsa

Diploma Tiga (DIII) Farmasi

Herman Herman, Akademi Farmasi Sandi Karsa

Diploma Tiga (DIII) Farmasi

References

Alta, U., Pratiwi, G., & Sari, L. Y. (2019). Formulasi Bedak Tabur Dari Ekstrak Lengkuas Merah (Alpinia purpurata K. Schum). Jurnal ’Aisyiyah Medika, 4. https://doi.org/10.36729/jam.v4i3.204

Asfi, D. (2018). Formulasi Bedak Tabur Antiseptik Ekstrak Daun Salam (Syzygium polyanthum (Wight.) Walp.) TERHADAP Staphylococcus aureus. Jurnal Kesehatan Yamasi, 2(1), Article 1.

http://jurnal.yamasi.ac.id/index.php/Jurkes/article/view/30

Dirjen POM. (1995). Farmakope Indonesia (Edisi IV). Departemen Kesehatan Republik Indonesia.

Fitriani, N., & Erlyn, P. (2019). Aktivitas Antidiabetik Kombinasi Ekstrak Etanol Daun Ciplukan (Physalis angulata) dan Daun Gaharu (Aquilaria malaccensis) pada Tikus Diabetes. Syifa’ MEDIKA: Jurnal Kedokteran Dan Kesehatan, 9(2), 70–78. https://doi.org/10.32502/sm.v9i2.1660

Harbone, J. B. (1987). Metode Fitokimia: Penuntun cara modern menganalisis tumbuhan terbitan kedua. ITB.

Hari, R., Sidiq, H. B. H. F., & Apriliyanti, I. P. (2018). Evaluasi Sifat Fisik Dan Uji Iritasi Gel Ekstrak Kulit Buah Pisang (Musa acuminata Colla). JCPS (Journal of Current Pharmaceutical Sciences), 2(1), 131–135.

Kurniawati, A., Mashartni, A., & Fauzia, I. S. (2016). Perbedaan khasiat anti jamur antara ekstrak etanol daun Kersen (Muntingia calabura L.) dengan nistatin terhadap pertumbuhan Candida albicans. Jurnal PDGI, 63(3).

http://jurnal.pdgi.or.id/index.php/jpdgi/article/view/147

Lau, S. H. A. (2019). Formulasi Dan Evaluasi Kestabilan Fisik Sediaan Gel Topikal Ekstrak Etanol Daun Ciplukan (Physalis angulata L.) Dengan Variasi Konsentrasi Karbopol 940 Serta Pengujian Hedoniknya. Jurnal Farmasi Sandi Karsa, 5(2), 120–126.

Pratiwi, N. S. (2018). Gambaran Kadar Vitamin C Pada Buah Ciplukan (Physalis Angulata L)(Studi Di Desa Candi Mulyo Kabupaten Jombang). In STIKES Insan Cendekia Medika. STIKES Insan Cendekia Medika Jombang.

Rahim, F. (2018). Formulasi Bedak Tabur Dari Ekstrak Rimpang Rumput Teki (Cyperus Rotundus L.) SEBAGAI ANTISEPTIK. Jurnal Ipteks Terapan, 12(1), 1–8. https://doi.org/10.22216/jit.2018.v12i1.2640

Ridwanuloh, D., & Syarif, F. (2019). Isolasi Dan Identifikasi Senyawa Flavonoid Dari Batang Ciplukan (Physalis angulata L.). Pharma Xplore : Jurnal Ilmiah Farmasi, 4(1), 288–296. https://doi.org/10.36805/farmasi.v4i1.619

Sutrisna, E. M. (2016). Herbal Medicine: Suatu Tujuan Farmakologis. In Ihsan (Ed.), Muhammadiyah University Press: Vol. VII. Muhammadiyah University Press.

Swandiyasa, K., Puspawati, N. M., & Asih, I. a. R. A. (2019). Potensi Ekstrak Daun Cendana (Santalum Album L.) Sebagai Senyawa Penghambat Jamur Candida albicans. Jurnal Kimia (Journal of Chemistry), 159–165.

https://doi.org/10.24843/JCHEM.2019.v13.i02.p06

Syamsuni, H. (2006). Farmasetika dasar dan hitungan farmasi. EGC.

Warnida, H., Masliyana, A., & Sapri, S. (2017). Formulasi Ekstrak Etanol Gambir (Uncaria Gambir Roxb.) Dalam Bedak Anti Jerawat. Jurnal Ilmiah Manuntung, 2(1), 99–106.

Widiyastuti, T. H. (2016). Uji aktivitas antifungi ekstrak etanol daun ciplukan (physalis angulata l), daun takokak (solanum torvum swartz), dan daun tomat (solanum lycopersicum l) terhadap pertumbuhan candida albicans. In UPT Perpustakaan Sebelas Maret. Universitas Sebelas Maret.

Wijanarko, A., Perawati, S., & Andriani, L. (2020). Standardisasi Simplisia Daun Ciplukan. Jurnal Farmasetis, 9(1), 31–40. https://doi.org/10.32583/farmasetis.v9i1.736

Published
2020-12-31
How to Cite
H. Ambo Lau, S., & Herman, H. (2020). Physical Stability Test of Leaf Powder Ethanol Extract of Ciplukan Leaf (Physalis angulata L.) as Anti-Fungal. Jurnal Ilmiah Kesehatan Sandi Husada, 9(2), 1117-1126. https://doi.org/10.35816/jiskh.v12i2.472

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