Musculoskeletal Complications in Diabetes Mellitus Patients
Dirga Yudha Prakasa
Abstract
Background. Apart from macrovascular and microvascular complications, diabetic patients may experience some musculoskeletal complications. The impact of musculoskeletal complications on the quality of life of diabetics is enormous. There are many epidemiological data linking this complication to diabetes, but the pathogenesis and causative factors have not been elucidated. Therefore, the aim of this literature study is to further investigate musculoskeletal complications in diabetes mellitus patients. Method. This study is a literature review, with 18 literature sources, from 1 national journal and 17 international journals. Result. Several studies have shown that musculoskeletal complications that are often found in people with diabetes mellitus include shoulder capsulitis, limited joint mobility syndrome, Dupuytren's contracture, carpal tunnel syndrome and trigger finger. Vascular and nerve damage, protein glycosylation, and increased collagen in the skin and musculoskeletal connective tissue are some of the factors thought to contribute to the development of musculoskeletal disorders in diabetics. Conclusion. The musculoskeletal manifestations of diabetes are common, and although they are not life threatening, they are an important cause of morbidity, pain and disability.
Keywords: diabetes mellitus, complications, musculoskeletal.
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References
Arsanjani Shirazi, A., Nasiri, M., & Yazdanpanah, L. (2016). Dermatological and musculoskeletal assessment of diabetic foot: A narrative review. Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 10(2), S158–S164. https://doi.org/10.1016/j.dsx.2016.03.004
Becker, J., Nora, D. B., Gomes, I., Stringari, F. F., Seitensus, R., Panosso, J. S., & Ehlers, J. A. C. (2002). An evaluation of gender, obesity, age and diabetes mellitus as risk factors for carpal tunnel syndrome. Clinical Neurophysiology, 113(9), 1429–1434.
https://doi.org/10.1016/S1388-2457(02)00201-8
Boswell, S. B., Patel, D. B., White, E. A., Gottsegen, C. J., Forrester, D. M., Masih, S., & Matcuk, G. R. (2014). Musculoskeletal manifestations of endocrine disorders. Clinical Imaging, 38(4), 384–396. https://doi.org/10.1016/j.clinimag.2014.02.014
Boyle, J. P., Thompson, T. J., Gregg, E. W., Barker, L. E., & Williamson, D. F. (2010). Projection of the year 2050 burden of diabetes in the US adult population: Dynamic modeling of incidence, mortality, and prediabetes prevalence. Population Health Metrics, 8, 1–12. https://doi.org/10.1186/1478-7954-8-29
Kiani, J., Goharifar, H., Moghimbeigi, A., & Azizkhani, H. (2014). Prevalence and risk factors of five most common upper extremity disorders in diabetics. Journal of Research in Health Sciences, 14(1), 93–96. https://doi.org/10.34172/jrhs141043
Lehuen, A., & Ph, D. (2015). A Double-Edged Sword against Type 1 Diabetes. New England Journal of Medicine, 372(8), 778.
Merashli, M., Chowdhury, T. A., & Jawad, A. S. M. (2015). Musculoskeletal manifestations of diabetes mellitus. Qjm, 108(11), 853–857. https://doi.org/10.1093/qjmed/hcv106
Molsted, S., Tribler, J., & Snorgaard, O. (2012). Musculoskeletal pain in patients with type 2 diabetes. Diabetes Research and Clinical Practice, 96(2), 135–140.
https://doi.org/10.1016/j.diabres.2011.12.022
Mooney, R. A., Sampson, E. R., Lerea, J., Rosier, R. N., & Zuscik, M. J. (2011). High-fat diet accelerates progression of osteoarthritis after meniscal/ligamentous injury. Arthritis Research and Therapy, 13(6). https://doi.org/10.1186/ar3529
Moseley, K. F. (2012). Type 2 diabetes and bone fractures. Current Opinion in Endocrinology, Diabetes and Obesity, 19(2), 128–135.
https://doi.org/10.1097/MED.0b013e328350a6e1
Mustafa, K. N., Khader, Y. S., Bsoul, A. K., & Ajlouni, K. (2016). Musculoskeletal disorders of the hand in type 2 diabetes mellitus: prevalence and its associated factors. International Journal of Rheumatic Diseases, 19(7), 730–735.
https://doi.org/10.1111/1756-185X.12617
Nichols, A. E. C., Oh, I., & Loiselle, A. E. (2020). Effects of Type II Diabetes Mellitus on Tendon Homeostasis and Healing. Journal of Orthopaedic Research, 38(1), 13–22. https://doi.org/10.1002/jor.24388
Pai, L. W., Hung, C. T., Li, S. F., Chen, L. L., Chung, Y. C., & Liu, H. L. (2015). Musculoskeletal pain in people with and without type 2 diabetes in Taiwan: A population-based, retrospective cohort study. BMC Musculoskeletal Disorders, 16(1), 1–7.
https://doi.org/10.1186/s12891-015-0819-4
Papanas, N., & Maltezos, E. (2010). The diabetic hand: a forgotten complication? Journal of Diabetes and Its Complications, 24(3), 154–162.
https://doi.org/10.1016/j.jdiacomp.2008.12.009
Ramchurn, N., Mashamba, C., Leitch, E., Arutchelvam, V., Narayanan, K., Weaver, J., Hamilton, J., Heycock, C., Saravanan, V., & Kelly, C. (2009). Upper limb musculoskeletal abnormalities and poor metabolic control in diabetes. European Journal of Internal Medicine, 20(7), 718–721.
https://doi.org/10.1016/j.ejim.2009.08.001
Saputri, R. D. (2020). Jurnal Ilmiah Kesehatan Sandi Husada ARTIKEL PENELITIAN Komplikasi Sistemik Pada Pasien Diabetes Melitus Tipe 2 Pendahuluan. 11(1), 230–236. https://doi.org/10.35816/jiskh.v10i2.254
Schett, G., Kleyer, A., Perricone, C., Sahinbegovic, E., Iagnocco, A., Zwerina, J., Lorenzini, R., Aschenbrenner, F., Berenbaum, F., D’Agostino, M. A., Willeit, J., & Kiechl, S. (2013). Diabetes is an independent predictor for severe osteoarthritis: Results from a longitudinal cohort study. Diabetes Care, 36(2), 403–409.
https://doi.org/10.2337/dc12-0924
Silva, M. B. G., & Skare, T. L. (2012). Musculoskeletal disorders in diabetes mellitus. Revista Brasileira de Reumatologia, 52(4), 601–605. https://doi.org/10.1590/S0482-50042012000400010
Singla, R., Gupta, Y., & Kalra, S. (2015). RECENT ADVANCES IN ENDOCRINOLOGY Musculoskeletal effects of diabetes mellitus. JPMA. The Journal of the Pakistan Medical Association, 65(9), 1024–1027. %5Cn%5Cn1.%5CnJPMA. The Journal of the Pakistan Medical Association1.%5CnJPMA. The Journal of the Pakistan Medical Association
Uhl, R. L., Rosenbaum, A. J., DiPreta, J. A., Desemone, J., & Mulligan, M. (2014). Diabetes mellitus: Musculoskeletal manifestations and perioperative considerations for the orthopaedic surgeon. Journal of the American Academy of Orthopaedic Surgeons, 22(3), 183–192. https://doi.org/10.5435/JAAOS-22-03-183
Varma, A. K. (2013). Charcot Neuroarthropathy of the Foot and Ankle: A Review. Journal of Foot and Ankle Surgery, 52(6), 740–749. https://doi.org/10.1053/j.jfas.2013.07.001
Yang, Y. L., Chee, W., & Im, E. O. (2019). Type 2 Diabetes and Musculoskeletal Symptoms Among Midlife Women. Diabetes Educator, 45(5), 520–528.
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