Consumption of Coffee to Prevent Alzheimer's Disease

Bimo Husodo

  • Bimo Husodo Universitas Lampung
Keywords: Alzheimer's disease, Beta-amyloid, Caffeine

Abstract

Coffee is one of the most consumed beverages in the world and most adults drink coffee every day. Coffee contains hundreds of bioactive compounds, including caffeine, chlorogenic acid, polyphenols, and small amounts of minerals and vitamins, which are known to have positive effects on brain health. Alzheimer's disease is a degenerative disease of the brain and the most common cause of dementia characterized by decreased memory, language, problem-solving, and other cognitive skills that affect a person's ability to perform daily activities. The purpose of this literature study is to determine the benefits of coffee consumption in preventing Alzheimer's disease. Method. This research is a literature study and library sources used involving 15 libraries from 1 national journal and 14 international journals. Result. Several studies have shown the preventive effects of coffee on Alzheimer's disease and cognitive decline through various mechanisms such as a role in lowering plasma Aβ levels, as well as an antioxidant that can reduce inflammation and protect against dementia. Conclusion. Coffee can have a protective effect on Alzheimer's disease and is safe to consume if it does not exceed the recommended dosage

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Author Biography

Bimo Husodo, Universitas Lampung

Progam studi pendidikan dokter

References

Arendash, G. W., & Cao, C. (2010). Caffeine and coffee as therapeutics against Alzheimer’s disease. Journal of Alzheimer’s Disease, 20(SUPPL.1), 117–126.

https://doi.org/10.3233/JAD-2010-091249

Cao, C., Cirrito, J. R., Lin, X., Wang, L., Verges, D. K., Dickson, A., Mamcarz, M., Zhang, C., Mori, T., Gary, W., Holtzman, D. M., & Potter, H. (2013). Alzheimer ’ s transgenic mice. 17(3), 681–697. https://doi.org/10.3233/JAD-2009-1071.Caffeine

Cao, C., Wang, L., Lin, X., Mamcarz, M., Zhang, C., Bai, G., Nong, J., Sussman, S., & Arendash, G. (2011). Caffeine synergizes with another coffee component to increase plasma GCSF: Linkage to cognitive benefits in Alzheimer’s mice. Journal of Alzheimer’s Disease, 25(2), 323–335. https://doi.org/10.3233/JAD-2011-110110

Carman, A. J., Dacks, P. A., Lane, R. F., Shineman, D. W., & Fillit, H. M. (2014). Current evidence for the use of coffee and caffeine to prevent age-related cognitive decline and Alzheimer’s disease. Journal of Nutrition, Health and Aging, 18(4), 383–392. https://doi.org/10.1007/s12603-014-0021-7

Eskelinen, M. H., & Kivipelto, M. (2010). Caffeine as a protective factor in dementia and Alzheimer’s disease. Journal of Alzheimer’s Disease, 20(SUPPL.1).

https://doi.org/10.3233/JAD-2010-1404

Gaugler, J., James, B., Johnson, T., Scholz, K., & Weuve, J. (2016). 2016 Alzheimer’s disease facts and figures. Alzheimer’s and Dementia, 12(4), 459–509.

https://doi.org/10.1016/j.jalz.2016.03.001

Higdon, J. V., & Frei, B. (2006). Coffee and health: A review of recent human research. Critical Reviews in Food Science and Nutrition, 46(2), 101–123. https://doi.org/10.1080/10408390500400009

Hu, N., Yu, J. T., Tan, L., Wang, Y. L., Sun, L., & Tan, L. (2013). Nutrition and the risk of alzheimer’s disease. BioMed Research International, 2013.

https://doi.org/10.1155/2013/524820

Kim, J. W., Byun, M. S., Yi, D., Lee, J. H., Jeon, S. Y., Jung, G., Lee, H. N., Sohn, B. K., Lee, J. Y., Kim, Y. K., Shin, S. A., Sohn, C. H., & Lee, D. Y. (2019). Coffee intake and decreased amyloid pathology in human brain. Translational Psychiatry, 9(1). https://doi.org/10.1038/s41398-019-0604-5

Pelligrino, D. A., Xu, H. L., & Vetri, F. (2010). Caffeine and the control of cerebral hemodynamics. Journal of Alzheimer’s Disease, 20(SUPPL.1), 1–16.

https://doi.org/10.3233/JAD-2010-091261

Sinyor, B., Mineo, J., & Ochner, C. (2020). Alzheimer’s Disease, Inflammation, and the Role of Antioxidants. Journal of Alzheimer’s Disease Reports, 4(1), 175–183. https://doi.org/10.3233/adr-200171

West, R. K., Ravona-Springer, R., Livny, A., Heymann, A., Shahar, D., Leroith, D., Preiss, R., Zukran, R., Silverman, J. M., & Schnaider-Beeri, M. (2019). Age modulates the association of caffeine intake with cognition and with gray matter in elderly diabetics. Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 74(5), 683–688. https://doi.org/10.1093/gerona/gly090

Wierzejska, R. (2017). Can coffee consumption lower the risk of Alzheimer’s disease and Parkinson’s disease? A literature review. Archives of Medical Science, 13(3), 507–514. https://doi.org/10.5114/aoms.2016.63599

Žĩ, Ğ., & Žī, Ś. (2011). SCIENCE OF MEDICINE Preventive Cardiology. December, 431–438.

Zulkifly, S., Darmawan, I., & Tambunan, V. (2017). Manfaat Kopi untuk Mencegah Penyakit Alzheimer. 44(10), 742–744.

Published
2020-12-31
How to Cite
Husodo, B. (2020). Consumption of Coffee to Prevent Alzheimer’s Disease. Jurnal Ilmiah Kesehatan Sandi Husada, 9(2), 996-1002. https://doi.org/10.35816/jiskh.v12i2.439

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