Konsumsi Cokelat Hitam Untuk Mencegah Preeklampsia
Lyliani Khairunnisa
Abstract
Background :Preeclampsia is a complication of pregnancy that has a high mortality and morbidity rate. Preeclampsia is characterized by new onset gestational hypertension and proteinuria. One theory regarding the mechanism of preeclampsia is endothelial dysfunction. Endothelial dysfunction causes decreased levels of nitric oxide. Objective :To find out more about consumption of dark chocolate to prevent preeclampsia Methods :Using literature studies from both national and international journals by summarizing the topic of discussion and comparing the results presented in the article. Results :Dark chocolate has high levels of flavonoids. Flavonoids in dark chocolate can help to increase levels of nitric oxide thus preventing endothelial dysfunction. Conclusion :Consumption of dark chocolate can prevent preeclampsia.
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References
Achamrah, N., & Ditisheim, A. (2018). Nutritional approach to preeclampsia prevention. In Current Opinion in Clinical Nutrition and Metabolic Care (Vol. 21, Issue 3, pp. 168–173). Lippincott Williams and Wilkins. https://doi.org/10.1097/MCO.0000000000000462
Ali, S. M., & Khalil, R. A. (2015). Genetic, immune and vasoactive factors in the vascular dysfunction associated with hypertension in pregnancy. In Expert Opinion on Therapeutic Targets (Vol. 19, Issue 11, pp. 1495–1515). Taylor and Francis Ltd. https://doi.org/10.1517/14728222.2015.1067684
Angsar, M. (2016). Ilmu Kebidanan (4th ed.). Bina Pustaka Sarwono Prawiroharjo.
Anto, E. O., Owiredu, W. K. B. A., Sakyi, S. A., Turpin, C. A., Ephraim, R. K. D., Fondjo, L. A., Obirikorang, C., Adua, E., & Acheampong, E. (2018). Adverse pregnancy outcomes and imbalance in angiogenic growth mediators and oxidative stress biomarkers is associated with advanced maternal age births: A prospective cohort study in Ghana. PLoS ONE, 13(7). https://doi.org/10.1371/journal.pone.0200581
Bokslag, A., van Weissenbruch, M., Mol, B. W., & de Groot, C. J. M. (2016). Preeclampsia; short and long-term consequences for mother and neonate. In Early Human Development (Vol. 102, pp. 47–50). Elsevier Ireland Ltd. https://doi.org/10.1016/j.earlhumdev.2016.09.007
Brandão, A. H. F., Félix, L. R., do Carmo Patrício, E., Leite, H. V., & Cabral, A. C. V. (2014). Difference of endothelial function during pregnancies as a method to predict preeclampsia. Archives of Gynecology and Obstetrics, 290(3), 471–477. https://doi.org/10.1007/s00404-014-3243-3
Carolia, N., Gde, L., & Ayuning, I. (2016). Ayuning dan Novita Carolia │Coklat Hitam untuk Mencegah Preeklampsia pada Kehamilan Majority | Volume 5 | Nomor 1 | Februari.
Chairunnisa, A., Putri, C., Dewi Puspitasari, R., & Prabowo, A. Y. (2017). Kematian Janin Intrauterin dan Hubungannya dengan Preeklampsia. Medula, 7(5), 62–65.
Cheng, C. M., Jalil, A. M. M., & Ismail, A. (2009). Phenolic and theobromine contents of commercial dark, milk and white chocolates on the Malaysian market. Molecules, 14(1), 200–209. https://doi.org/10.3390/molecules14010200
Correa, P. J., Palmeiro, Y., Soto, M. J., Ugarte, C., & Illanes, S. E. (2016). Etiopathogenesis, prediction, and prevention of preeclampsia. In Hypertension in Pregnancy (Vol. 35, Issue 3, pp. 280–294). Taylor and Francis Ltd. https://doi.org/10.1080/10641955.2016.1181180
Cunningham, F., Leveno, K., Bloom, S., Hauth, J., Spong, C., & Rouse, D. (2010). Obstetri Williams (23rd ed.). McGraw-Hill Companies.
Echeverri, I., Ortega-Ávila, J. G., Mosquera, M., Castillo, A., Jiménez, E., Suárez-Ortegon, M. F., Mateus, J. C., & Aguilar-de Plata, C. (2015). Relationship between maternal and newborn endothelial function and oxidative stress. American Journal of Human Biology, 27(6), 822–831. https://doi.org/10.1002/ajhb.22733
Fantasia, H. C. (2018). Low-Dose Aspirin for the Prevention of Preeclampsia. In Nursing for Women’s Health (Vol. 22, Issue 1, pp. 87–92). Elsevier B.V. https://doi.org/10.1016/j.nwh.2017.12.002
Flammer, A. J., Hermann, F., Sudano, I., Spieker, L., Hermann, M., Cooper, K. A., Serafini, M., Lüscher, T. F., Ruschitzka, F., Noll, G., & Corti, R. (2007). Dark chocolate improves coronary vasomotion and reduces platelet reactivity. Circulation, 116(21), 2376–2382. https://doi.org/10.1161/CIRCULATIONAHA.107.713867
Gammone, M. A. (2018). Impact of chocolate on the cardiovascular health. Frontiers in Bioscience, 23(3), 4620. https://doi.org/10.2741/4620
Higginbotham, E., & Taub, P. R. (2015). Cardiovascular Benefits of Dark Chocolate? In Current Treatment Options in Cardiovascular Medicine (Vol. 17, Issue 12). Springer Healthcare. https://doi.org/10.1007/s11936-015-0419-5
Hooper, L., Kay, C., Abdelhamid, A., Kroon, P. A., Cohn, J. S., Rimm, E. B., & Cassidy, A. (2012). Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: A systematic review and meta-analysis of randomized trials. American Journal of Clinical Nutrition, 95(3), 740–751. https://doi.org/10.3945/ajcn.111.023457
Koli, R., Köhler, K., Tonteri, E., Peltonen, J., Tikkanen, H., & Fogelholm, M. (2015). Dark chocolate and reduced snack consumption in mildly hypertensive adults: An intervention study. Nutrition Journal, 14(1). https://doi.org/10.1186/s12937-015-0075-3
Mogollon, J. A., Boivin, C., Philippe, K., Turcotte, S., Lemieux, S., Blanchet, C., Bujold, E., & Dodin, S. (2013). Consumption of chocolate in pregnant women and risk of preeclampsia: a systematic review. http://www.systematicreviewsjournal.com/content/2/1/114
Montagna, M. T., Diella, G., Triggiano, F., Caponio, G. R., de Giglio, O., Caggiano, G., di Ciaula, A., & Portincasa, P. (2019). Chocolate, “food of the gods”: History, science, and human health. In International Journal of Environmental Research and Public Health (Vol. 16, Issue 24). MDPI AG. https://doi.org/10.3390/ijerph16244960
Paauw, N. D., & Lely, A. T. (2018). Cardiovascular sequels during and after preeclampsia. In Advances in Experimental Medicine and Biology (Vol. 1065, pp. 455–470). Springer New York LLC. https://doi.org/10.1007/978-3-319-77932-4_28
Triche, E. W., Grosso, L. M., Belanger, K., Darefsky, A. S., Benowitz, N. L., & Bracken, M. B. (2008). Chocolate consumption in pregnancy and reduced likelihood of preeclampsia. Epidemiology, 19(3), 459–464. https://doi.org/10.1097/EDE.0b013e31816a1d17
Verna, R. (2013). The history and science of chocolate. Malays J Pathol, 35, 111–121.
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