Enzim Transferase dengan Bilirubin Total Penderita Ikterus Obstruktif

Fatima Maulidina Fajrian

  • Fatima Maulidina Fajrian Universitas Malahayati
Keywords: SGOT/SGPT, Total Bilirubin, Obstructive Jaundice

Abstract

Post-hepatic obstructive jaundice is jaundice that caused by an obstruction in the bile ducts that leads to disruption of bile flow between the liver and duodenum. The function of the liver can be measured by examining the activity of serum aminotransferase, known as Serum Glutamic Oxaloacetic Transaminase and Serum Glutamic Pyruvic Transaminase. SGOT, SGPT, and bilirubin is one of the liver productions in which if liver damage occurs, there will be abnormalities in the results. The purpose of this study was to determine the relationship between transferase enzymes and total bilirubin in obstructive jaundice patients. This study was an Observational analytic approach with a cross-sectional design, and the sampling technique was purposive sampling and obtained a sample of 40 people. Patients data were obtained from secondary data with medical records. The bivariate test is done by Spearman’s correlation test. The result showed that there is a good correlation between SGOT levels and total bilirubin levels (p-value = 0.001), with a correlation value of 0.498, also SGPT levels and total bilirubin levels (p-value = 0.011), with a correlation value of 0.397. The conclusion is an increase of total bilirubin levels in obstructive jaundice patients will be accompanied by an increase of SGOT and SGPT levels

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Author Biography

Fatima Maulidina Fajrian, Universitas Malahayati

Pendidikan Dokter, Fakultas Kedokteran

References

Abdoerrachman, M.H. et al. (2007). Buku Kuliah Ilmu Kesehatan Anak Jilid 2. Jakarta: Bagian Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Indonesia.

Arief, Sjamsul. Deteksi Dini Kolestasis Neonatal. Surabaya; FK UNAIR/ RSU Dr Soetomo. Diunduh dari http://www.pediatrik.com/pkb/20060220ena504-pkb.pdf diakses 2 okt 2011

Aleya, A., & Berawi, K. (2015). Korelasi Pemeriksaan Laboratorium SGOT/SGPT dengan Kadar Bilirubin pada Pasien Hepatitis C di Ruang Penyakit Dalam RSUD Dr. H. Abdul Moeloek Provinsi Lampung pada Bulan Januari-Desember 2014. Jurnal Majority, 4(9), 135-139.

Brama, Ragil. (2013). Karakteristik Dan Evaluasi Kadar Bilirubin Direct Pre-Operatif Dan Post-Operatif Pada Pasien Ikterik Obstruksi Post-Hepatik. Jurnal Kedokteran Universitas Jambi.

Burleigh BA, Favre DS. (2008). Molecular Mechanism of Parasite Invasion. Science;. p.192. Springer, USA.

Dorland. (1998). Kamus Saku Kedokteran Dorland. Jakarta: EGC.

Dorland WA, Newman. (2008). Kamus Kedokteran Dorland edisi 31. Jakarta: Penerbit Buku Kedokteran EGC. p. 702, 1003.

Fajil A, Vernekar PV, Geriani D. (2013). Clinical profile and comlication of malaria hepatopathy. 5:383-8.

Garba, I. H., & Gregory, U. (2006). AST/ALT ratio in acute, uncomplicated falciparum malaria infection: Comparison in relation to the AST/ALT ratios in diseases of the liver. Internet J Anesthesiol, 14(2).

Guyton, Arthur C dan John E hall. (1997). Fisiologi Gastrointestinal. Dalam : Irawati Setiawan (Editor Bahasa Indonesia) Buku Ajar Fisiologi Kedokteran Edisi 9. Jakarta: EGC. h. 1108-1109

Kee, Joyce LeFever. (1997). Buku Saku Pemeriksaan Laboratorium dan Diagnostik Dengan Implikasi Keperawatan. Jakarta : EGC.

Ringoringo, Parlin dr. (1990). Atresia Bilier dalam Cermin Dunia Kedokteran No. 86, 1993. Jakarta: Jurnal diunduh dari

http://www.kalbe.co.id/files/cdk/files/cdk_086_masalah_anak.pdf

Sacher, R.A., dan McPherson, R.A. (2002). Tinjauan Klinis Hasil Pemeriksaan Laboratorium Cetakan 1. Jakarta: Penerbit Buku Kedokteran EGC.

Sardjono, T. W, Ismanoe G dan E. Widjayanto. (2004). The Role Of Laboratory Medicine In Diagnosis And Tropical And Infectious Disease Patients. Jurnal Kedokteran Brawijaya. April. 20(1).

Schwarz SM. (2011). Pediatric biliary atresia. [online]. Updated Juni 2011. [cited September 2011]. Available from URL:

https://emedicine.medscape.com/article/927029-overview

Smeltzer, S.C., dan Bare, B.G. (2002). Buku Ajar Keperawatan Medikal Bedah Brunner& Suddarth Edisi 8 Vol. 2. Jakarta: Penerbit Buku Kedokteran EGC.

Spiritia. (2008). Strategi Nasional Penanggulangan HIV/AIDS. Diakses pada tanggal 30 Oktober 2015. From : http;//spiritia.or.id/art/pdf/a1056.pdfhtm.

Sulaiman HA, Akbar HN, Lesmana LA, Noer HMS. (2009). Buku ajar ilmu penyakit hati. Edisi ke-1 (Revisi). Jakarta: Jayabadi.

Sulaiman, Ali. (2007). Pendekatan klinis pada pasien ikterus. In: Aru W Sudoyo, et al. Buku ajar ilmu penyakit dalam Jilid 1. 5th Ed. Jakarta: Penerbitan FKUI; p.420-3.

Wibowo, S. (2007). Perbandingan kadar bilirubin neonatus dengan dan tanpa defisiensi glucose-6-phosphate dehydrogenase, infeksi dan tidak infeksi. Diss. Program Pasca Sarjana Universitas Diponegoro, Semarang.

Wong DL. Buku Ajar Keperawatan Pediatrik Volume 1. Jakarta: EGC;2008. p.422.

Published
2020-06-30
How to Cite
Fajrian, F. (2020). Enzim Transferase dengan Bilirubin Total Penderita Ikterus Obstruktif. Jurnal Ilmiah Kesehatan Sandi Husada, 11(1), 176-182. https://doi.org/10.35816/jiskh.v11i1.240
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