Rasio Neutrofil Limfosit Sebagai Prediktor Tingkat Keparahan Stroke Iskemik

Thaharatin Giza Wulandari

  • Thaharatin Giza Wulandari Universitas Lampung
Keywords: Rasio Neutrofit limfosit, Stroke iskemik, Inflamasi


Among the several types of strokes, ischemic stroke has the highest incidence of about 80% to 85% and is characterized by a disruption in blood flow in the brain. There are many inflammatory markers identified as possible predictors of prognosis in ischemic stroke. Compared to other inflammatory markers, leukocyte counts are the most widely used and simplest. Neutrophils and lymphocytes are the main components in leukocytes. The neutrophil lymphocyte ratio has been proposed as an easy parameter to assess a person's inflammatory status. The neutrophil lymphocyte ratio can reflect an imbalance between overactive inflammation and protective reagulation and has advantages over using neutrophils or lymphocytes alone. The neutrophil lymphocyte ratio is easy to obtain, noninvasive, and one of the inexpensive markers of inflammation, and can be used routinely to indicate the status of systematic inflammation in clinical work.


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Author Biography

Thaharatin Giza Wulandari, Universitas Lampung

Program Pendidikan Dokter Fakultas Kedokteran


Aytaç, E., Akpinar, Ç. K., Gürkaş, E., Numune, A., Hastanesi, A., & K, N. (2017). Neutrophil to Lymphocyte Ratio : A Simple and Readily Available Independent Marker of Mortality in Acute Ischemic Stroke, 22(4), 192–196.

Balta, S., Celik, T., Mikhailidis, D. P., Ozturk, C., Demirkol, S., Aparci, M., & Iyisoy, A. (2016). The Relation Between Atherosclerosis and the Neutrophil – Lymphocyte Ratio.

Bratawidjaja, K. G., & Rengganis, I. (2016). Imunologi Dasar (11th ed.). Jakarta: Badan Penerbit Fakultas Kedokteran Universitas Indonesia.

Kim, M. K., Lee, J. H., & Yoo, B. G. (2017). Neutrophil to Lymphocyte Ratio Predicts Short-Term Functional Outcome in Acute Ischemic Stroke, 2(3), 30–37.

Lattanzi, S., Brigo, F., Trinka, E., Cagnetti, C., Napoli, M. Di, & Silvestrini, M. (2018). Neutrophil-to-Lymphocyte Ratio in Acute Cerebral Hemorrhage : a System Review.

Planas, A. M. (2018). Role of Immune Cells Migrating to the Ischemic Brain, 1–7. RISKESDAS. (2013). Penyakit yang ditularkan melalui udara. Jakarta: Badan Penelitian Dan Pengembangan Kesehatan Departemen Kesehatan Republik Indonesia, (Penyakit Menular),103.

Ruhnau, J., Schulze, J., Dressel, A., & Vogelgesang, A. (2017). Thrombosis , Neuroinflammation , and Poststroke Infection : The Multifaceted Role of Neutrophils in Stroke, 2017.

Song, S., Zhao, X., Rajah, G., Hua, C., & Kang, R. (2019). Clinical Significance of Baseline Neutrophil-to-Lymphocyte Ratio in Patients With Ischemic Stroke or Hemorrhagic Stroke : An Updated, 10(October).

Sun, Y., You, S., Zhong, C., Huang, Z., & Hu, L. (2016). American Journal of Emergency Medicine Neutrophil to lymphocyte ratio and the hematoma volume and stroke severity in acute intracerebral hemorrhage patients. American Journal of Emergency Medicine.

Tokgoz, S., Kayrak, M., Akpinar, Z., & Figen, G. (2013). Neutrophil Lymphocyte Ratio as a Predictor of Stroke € l Y u Abdullah Seyithano g, 22(7), 1169–1174.

Wang, L., Song, Q., Wang, C., Wu, S., Deng, L., Li, Y., & Zheng, L. (2019). Journal of the Neurological Sciences Neutrophil to lymphocyte ratio predicts poor outcomes after acute ischemic stroke : A cohort study and systematic review. Journal of the Neurological Sciences, 406(May), 116445.

Ye, Z., Ai, X., Fang, F., Hu, X., & Faramand, A. (2017). The prediction of neutrophil to lymphocyte ratio for outcomes in ischemic stroke.

Zhang, J., Ren, Q., Song, Y., He, M., Zeng, Y., Liu, Z., & Xu, J. (2017). Prognostic role of neutrophil – lymphocyte ratio in patients with acute ischemic stroke, 1–5.

How to Cite
Wulandari, T. (2019). Rasio Neutrofil Limfosit Sebagai Prediktor Tingkat Keparahan Stroke Iskemik. Jurnal Ilmiah Kesehatan Sandi Husada, 10(2), 217-221. Retrieved from https://akper-sandikarsa.e-journal.id/JIKSH/article/view/153